Daganatos sejtek reakciója, apoptózis, sejthalál – Publikációk

1.

Active Hexose Correlated Compound (AHCC) promotes an intestinal immune response in BALB/c mice and in primary intestinal epithelial cell culture involving toll-like receptors TLR-2 and TLR-4.

Mallet JF, Graham É, Ritz BW, Homma K, Matar C.

Eur J Nutr. 2015 Jan 18. [Epub ahead of print]

PMID: 25596849

2.

A natural immune modulator attenuates stress hormone and catecholamine concentrations in polymicrobial peritonitis.

Love KM, Barnett RE, Holbrook I, Sonnenfeld G, Fujii H, Sun B, Peyton JC, Cheadle WG.

J Trauma Acute Care Surg. 2013 Jun;74(6):1411-8. doi: 10.1097/TA.0b013e31829215b1.

PMID: 23694866

3.

Genotoxicity and subchronic toxicity evaluation of Active Hexose Correlated Compound (AHCC).

Fujii H, Nishioka N, Simon RR, Kaur R, Lynch B, Roberts A.

Regul Toxicol Pharmacol. 2011 Mar;59(2):237-50. doi: 10.1016/j.yrtph.2010.10.006. Epub 2010 Oct 14.

PMID: 20951179

4.

Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-γ and/or tumor necrosis factor-α in healthy adults.

Yin Z, Fujii H, Walshe T.

Hum Immunol. 2010 Dec;71(12):1187-90. doi: 10.1016/j.humimm.2010.08.006. Epub 2010 Aug 21.

PMID: 20732368

5.

Melanoma:

Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model.

Ignacio RM, Kim CS, Kim YD, Lee HM, Qi XF, Kim SK.

Cytokine. 2015 Dec;76(2):131-7. doi: 10.1016/j.cyto.2015.06.002. Epub 2015 Jun 13.

PMID: 26082022

6.

Melanoma

Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model.

Ignacio RM, Kim CS, Kim YD, Lee HM, Qi XF, Kim SK.

Cytokine. 2015 Dec;76(2):131-7. doi: 10.1016/j.cyto.2015.06.002. Epub 2015 Jun 13.

PMID: 26082022

7.

The use of mushroom glucans and proteoglycans in cancer treatment.

Kidd PM.

Altern Med Rev. 2000 Feb;5(1):4-27. Review.

PMID: 10696116

8.

Hasnyálmirigyrák

Active Hexose-correlated Compound Down-regulates Heat Shock Factor 1, a Transcription Factor for HSP27, in Gemcitabine-resistant Human Pancreatic Cancer Cells.

Tokunaga M, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.

Anticancer Res. 2015 Nov;35(11):6063-7.

PMID: 26504030

9.

Hasnyálmirigyrák

Active hexose-correlated compound down-regulates sex-determining region Y-box 2 of pancreatic cancer cells.

Nawata J, Kuramitsu Y, Wang Y, Kitagawa T, Tokuda K, Baron B, Akada J, Suenaga S, Kaino S, Maehara S, Maehara Y, Sakaida I, Nakamura K.

Anticancer Res. 2014 Sep;34(9):4807-11.

PMID: 25202061

10.

Májrák

Evaluating the role of treatment-related toxicities in the challenges facing targeted therapies for advanced hepatocellular carcinoma.

Palmer DH, Johnson PJ.

Cancer Metastasis Rev. 2015 Sep;34(3):497-509. doi: 10.1007/s10555-015-9580-2.

PMID: 26250585

Májrák

Sorafenib and hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombus.

Nagai H, Mukozu T, Ogino YU, Matsui D, Matsui T, Wakui N, Momiyama K, Igarashi Y, Sumino Y, Higai K.

Anticancer Res. 2015 Apr;35(4):2269-77.

PMID: 25862889

12.

Májrák

VEGF in patients with advanced hepatocellular carcinoma receiving intra-arterial chemotherapy.

Matsui D, Nagai H, Mukozu T, Ogino YU, Sumino Y.

Anticancer Res. 2015 Apr;35(4):2205-10.

PMID: 25862879

13.

Májrák

Anti-tumor activity of sorafenib in a model of a pediatric hepatocellular carcinoma.

Nagel C, Armeanu-Ebinger S, Dewerth A, Warmann SW, Fuchs J.

Exp Cell Res. 2015 Feb 1;331(1):97-104. doi: 10.1016/j.yexcr.2014.10.018. Epub 2014 Oct 31.

PMID: 25447203

14.

Májrák

Importance of branched-chain amino acids in patients with liver cirrhosis and advanced hepatocellular carcinoma receiving hepatic arterial infusion chemotherapy.

Kanekawa T, Nagai H, Kanayama M, Sumino Y.

Cancer Chemother Pharmacol. 2014 Nov;74(5):899-909. doi: 10.1007/s00280-014-2564-z. Epub 2014 Aug 20.

PMID: 25138286

15.

Májrák

Neutrophil-to-lymphocyte ratio acts as a prognostic factor for patients with advanced hepatocellular carcinoma.

Li X, Chen ZH, Ma XK, Chen J, Wu DH, Lin Q, Dong M, Wei L, Wang TT, Ruan DY, Lin ZX, Xing YF, Deng Y, Wu XY, Wen JY. Tumour Biol. 2014 Nov;35(11):11057-63. doi: 10.1007/s13277-014-2360-8. Epub 2014 Aug 6.

PMID: 25095975

16.

Májrák

Changes of cytokines in patients with liver cirrhosis and advanced hepatocellular carcinoma treated by sorafenib.

Nagai H, Kanekawa T, Kobayashi K, Mukozu T, Matsui D, Matsui T, Kanayama M, Wakui N, Momiyama K, Shinohara M, Ishii K, Igarashi Y, Sumino Y. Cancer Chemother Pharmacol. 2014 Feb;73(2):223-9. doi: 10.1007/s00280-013-2344-1. Epub 2013 Nov 13.

PMID: 24220937

17.

Májrák

Sorafenib prevents escape from host immunity in liver cirrhosis patients with advanced hepatocellular carcinoma.

Nagai H, Mukozu T, Matsui D, Kanekawa T, Kanayama M, Wakui N, Momiyama K, Shinohara M, Iida K, Ishii K, Igarashi Y, Sumino Y. Clin Dev Immunol. 2012;2012:607851. doi: 10.1155/2012/607851. Epub 2012 May 14.

PMID: 22666283 Free PMC Article

18.

Májrák

Phase II trial of sorafenib in combination with 5-fluorouracil infusion in advanced hepatocellular carcinoma.

Petrini I, Lencioni M, Ricasoli M, Iannopollo M, Orlandini C, Oliveri F, Bartolozzi C, Ricci S.

Cancer Chemother Pharmacol. 2012 Mar;69(3):773-80. doi: 10.1007/s00280-011-1753-2. Epub 2011 Oct 28.

PMID: 22033636

19.

Mellrák, emlőrák

Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.

Haidari M, Zhang W, Wakame K.

Life Sci. 2013 Dec 18;93(25-26):994-1003. doi: 10.1016/j.lfs.2013.10.027. Epub 2013 Nov 6.

PMID: 24211779

20.

Mellrák, emlőrák

Effect of active hexose-correlated compound in women receiving adjuvant chemotherapy for breast cancer: a retrospective study.

Hangai S, Iwase S, Kawaguchi T, Kogure Y, Miyaji T, Matsunaga T, Nagumo Y, Yamaguchi T. J Altern Complement Med. 2013 Nov;19(11):905-10. doi: 10.1089/acm.2012.0914. Epub 2013 Jul 5.

PMID: 23829813 Free PMC Article

21.

Hashártyagyulladás

A natural immune modulator attenuates stress hormone and catecholamine concentrations in polymicrobial peritonitis.

Love KM, Barnett RE, Holbrook I, Sonnenfeld G, Fujii H, Sun B, Peyton JC, Cheadle WG.

J Trauma Acute Care Surg. 2013 Jun;74(6):1411-8. doi: 10.1097/TA.0b013e31829215b1.

PMID: 23694866

22.

Prosztatarák

Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer.

Turner J, Chaudhary U.

Anticancer Drugs. 2009 Mar;20(3):215-6. doi: 10.1097/CAD.0b013e3283163c26.

PMID: 19104437

23.

The use of mushroom glucans and proteoglycans in cancer treatment.

Kidd PM.

Altern Med Rev. 2000 Feb;5(1):4-27. Review.

PMID: 10696116